We present diffusion and anatomical (T1w) processed data and derivatives from a group of IU athletes (football, cross-country) and non-athletes (students). The raw data contains both anatomical (T1 weighted) and diffusion-weighted (dMRI) magnetic resonance imaging data. The processed data shares 14 types of derivatives across 42 participants, comprising of 84 brainmasks (2 per participant), 42 Freesurfer outputs (1 per participant), 168 fiber orientation dispersion (FOD) images (4 per participant), 588 diffusion parameter maps (14 per participant), 42 tractograms (1 per participant), 2562 segmented major tracts (61 per participant), and 756 connectivity matrices (18 per participant).